Pure 5 Amino-1 Mq

Pure 5 Amino-1 Mq

Product name:Pure 5 Amino-1 mq
Other name:5-Amino-1-methylquinolinium iodide (NNMT inhibitor)
Specification:99%
MOQ:g
Sample: Available
Appearance: Red powder
Stock: In Stock
Customization: Support (custom dosage, capsule size, bulk packaging)
Storage:Store in a sealed, dry place, protected from light
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Description
Technical Parameters

Products Description

 

Pure 5 Amino-1 mq is a high-purity, active molecule intended for research use, primarily functioning as a selective inhibitor of a metabolic enzyme found in the body known as NNMT (Nicotinamide N-methyltransferase). By inhibiting NNMT, this molecule elevates intracellular levels of NAD+, thereby activating signaling pathways associated with energy metabolism. In animal studies, it has demonstrated two primary effects: first, promoting the breakdown of adipose tissue, which aids in reducing body weight and blood lipid levels; and second, supporting the function of muscle stem cells, thereby facilitating the repair of damaged muscle tissue. These characteristics have garnered significant interest in the fields of metabolic regulation and tissue regeneration.

 

Pure 5 Amino-1 mq

 

Product Function

 

Pure 5 Amino-1 mq regulates intracellular NAD+ levels-and subsequently influences energy metabolism and tissue repair processes-by selectively inhibiting the activity of NNMT (Nicotinamide N-methyltransferase) within the body. NNMT is highly expressed in adipose tissue and aging muscle; its overactivity leads to the excessive depletion of nicotinamide, resulting in a decline in NAD+ levels. By inhibiting NNMT, this molecule helps restore the availability of NAD+, thereby indirectly activating signaling pathways associated with metabolism and repair. This molecule exerts its effects primarily in two physiological domains:

 

  • Regulation of Lipid Metabolism

      In animal models, this molecule effectively reduces the accumulation of white adipose tissue and lowers total cholesterol levels. Notably, this effect is independent of changes in appetite, suggesting that its mechanism of action is directly linked to the basal metabolic rate. Specifically, observations include a reduction in adipocyte volume and a decrease in epididymal fat mass, without any concomitant changes in feeding behavior. This mode of metabolic regulation-which operates independently of appetite control-lends it unique research value within the field of weight management.

 

Pure 5 Amino-1 mq for weight

 

  • Support for Muscle Tissue

      In models involving aging or injury-related muscle conditions, this molecule enhances the proliferative capacity of muscle stem cells and promotes the fusion and repair of muscle fibers following injury, thereby aiding in the maintenance of muscle mass. The decline in muscle regenerative capacity observed in aging individuals is partly attributed to reduced muscle stem cell activity; by modulating NAD+ metabolism, this molecule helps restore the activation potential of these stem cells, thereby accelerating the process of muscle fiber reconstruction at injury sites.

 

The following table summarizes the observed results of this product across different research directions, with all data derived from animal experiments:

Research Direction Observation Indicator Result Description
Weight Control Body Weight Change Approximately 5.1% decrease in body weight over 11 days, while the control group showed a 1.4% increase during the same period
Adipose Tissue Epididymal Fat Mass Approximately 35% reduction in fat tissue mass
Cellular Level Adipocyte Volume Average adipocyte volume reduced by more than 30%
Blood Lipids Total Cholesterol Approximately 30% reduction in levels
Muscle Regeneration Active Muscle Stem Cell Count Increased by 60%-75% (depending on dosage)

 

Quality Control

 

1.Typical COA Testing Parameters

Test Item Specification Result
Appearance Red powder Conforms
Identification Positive reaction Conforms
Assay ≥98.0% 98.6%
Individual Impurity ≤0.1% 0.02%
Total Impurities ≤0.5% 0.03%
Loss on Drying ≤1.0% 0.12%
Residue on Ignition ≤0.1% 0.05%
Heavy Metals ≤10ppm Conforms

 

2.The following table lists the main quality control parameters and their corresponding testing methods:

Quality Control Parameter Specification Testing Method
Assay ≥98% High Performance Liquid Chromatography (HPLC)
Related Substances (Individual Impurity) ≤0.5% High Performance Liquid Chromatography (HPLC)
Related Substances (Total Impurities) ≤1.0% High Performance Liquid Chromatography (HPLC)
Loss on Drying ≤1.5% Gravimetric Drying Method (EP 2.2.32)
Residue on Ignition ≤0.3% Gravimetric Ignition Method (EP 2.4.16)
Total Heavy Metals ≤10 ppm Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
Microbial Limits Aerobic bacteria ≤100 CFU/g Plate Count Method (USP <61>)
Endotoxins ≤0.5 EU/mg Limulus Amebocyte Lysate Test (LAL Test, USP <85>)

Note: Each batch of the product is accompanied by a batch-specific Certificate of Analysis (COA), available upon request. Storage conditions: 2-8°C, sealed, protected from light. The shelf life is 24 months under unopened conditions.

 

Logistics and Packaging

Pure 5 Amino-1 mq utilizes a professional packaging and logistics system to ensure the stability and integrity of the product during transit and storage. All packaging materials comply with transport regulations for research-grade chemicals, and customized logistics solutions can be provided to meet specific client requirements.

 

logistics and packaging

 

  • Packaging Specifications

The inner packaging consists of sealed, moisture-proof aluminum foil bags that provide light protection, with each bag constituting a single standard unit. The outer packaging utilizes custom-designed cardboard boxes or foam containers to provide physical protection and cushioning, safeguarding against compression and vibration during transit. For orders requiring cold-chain transport, ice packs or dry ice can be added to ensure the product remains within a temperature range of 2–8°C or -20°C during shipment.

 

  • Logistics and Delivery

We partner with leading international carriers, including DHL, FedEx, UPS, TNT, and EMS. Ambient-temperature shipping is suitable for short-distance transit scenarios, while cold-chain shipping can be customized according to client needs. In-stock orders are dispatched within 24 hours, while bulk orders are shipped within one week. A tracking number is provided for every order, allowing for end-to-end shipment monitoring; international express shipments typically arrive within 5 to 7 business days.

 

  • Packaging Features

All products are enclosed in tamper-evident, sealed packaging to ensure that the product remains unopened during transit. The exterior of the packaging features product identification labels and batch numbers, fully complying with international shipping labeling standards.

 

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